Progressive postoperative atrophy of ipsilateral thalamus, putamen, and globus pallidus in patients with temporal lobe epilepsy: A volumetric analysis
We studied 100 patients with epilepsy, comparing those who had surgery to those who did not. After surgery, the thalamus, putamen and globus pallidus on the same side as the surgery shrank significantly, but not in non-surgery patients. This suggests surgery-related changes in deeper brain structures, unrelated to seizure freedom or cognitive outcomes. This research sheds additional light on the response of the subcortical structure to epilepsy surgery, highlighting potential areas for further study.
Authors
- Dragoslav Sokić (ORCID: https://orcid.org/0000-0003-0226-9727)
- Aleksa Pejović (ORCID: https://orcid.org/0000-0003-1721-6011)
- Marko Daković (ORCID: https://orcid.org/0000-0001-7455-5584)
- Nikola Vojvodić (ORCID: https://orcid.org/0000-0002-8433-0319)
- Aleksandar J. Ristić (ORCID: https://orcid.org/0000-0002-7564-1641)
- Zorica Joković (ORCID: https://orcid.org/0000-0001-7073-3857)
- Matthias J. Koepp (ORCID: https://orcid.org/0000-0002-4277-8000)
- Vladimir Baščarević (ORCID: https://orcid.org/0000-0002-1490-4567)
- Marija Jovanović
Institutions
- University of Belgrade (RS)
- Centar za Promociju Nauke (RS)
- University Children's Hospital, Belgrade (RS)
- University College London (GB)
Publication Details
- Journal
- Epilepsia Open
- Published
- 2024-10-28
- DOI
- https://doi.org/10.1002/epi4.13088
- Primary Topic
- Epilepsy research and treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00