Postural control in episodic ataxia type 2: no evidence for increased vestibular excitability
The larger postural unsteadiness of EA2 patients probably reflects their progressive cerebellar degeneration. It is not related to abnormal visual (Romberg's ratio) or proprioceptive control of stance. Postural unsteadiness during vestibular stimulation does not indicate altered vestibular excitability in EA2 patients. However, vestibular stimulation increasingly destabilized postural control of EA2 patients with higher motion perception thresholds when proprioceptive information was diminished. This conclusion, however, is restricted to the postural control of EA2 patients in the interval between the vestibulo-cerebellar episodes.
Authors
- Christos Ganos (ORCID: https://orcid.org/0000-0001-8077-8530)
- Matthis Synofzik (ORCID: https://orcid.org/0000-0002-2280-7273)
- Christoph Helmchen (ORCID: https://orcid.org/0000-0003-2493-2294)
- Andreas Sprenger (ORCID: https://orcid.org/0000-0001-9255-7911)
- Dagmar Timmann (ORCID: https://orcid.org/0000-0003-1935-416X)
- Janina von der Gablentz (ORCID: https://orcid.org/0000-0003-0647-5923)
- Norbert Brüggemann (ORCID: https://orcid.org/0000-0001-5969-6899)
- Nina Overbeeke
Institutions
- Toronto Western Hospital (CA)
- German Center for Neurodegenerative Diseases (DE)
- University Hospital Schleswig-Holstein (DE)
- Essen University Hospital (DE)
- Hertie Institute for Clinical Brain Research (DE)
- University of Duisburg-Essen (DE)
- University of Tübingen (DE)
- University of Lübeck (DE)
Publication Details
- Journal
- European Journal of Neurology
- Published
- 2024-10-27
- DOI
- https://doi.org/10.1111/ene.16520
- Citations
- 1
- Primary Topic
- Vestibular and auditory disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.25
Funders
- Deutsche Forschungsgemeinschaft
- Universität zu Lübeck