Exploring tumor endothelial cells heterogeneity in hepatocellular carcinoma: insights from single-cell sequencing and pseudotime analysis
The study revealed the heterogeneity of TECs in HCC and their potential roles in tumor progression, offering new perspectives and potential therapeutic targets for HCC molecular mechanisms. The findings emphasize the importance of further exploring TECs heterogeneity for understanding HCC pathogenesis and developing personalized treatment strategies.
Authors
- Kaijie Liu (ORCID: https://orcid.org/0000-0001-9099-8713)
- Xinyu Gu (ORCID: https://orcid.org/0000-0001-9232-8844)
- Yafeng Liu (ORCID: https://orcid.org/0000-0003-3930-4872)
- Jiachun Sun (ORCID: https://orcid.org/0000-0003-4424-5010)
- Shujun Zhang (ORCID: https://orcid.org/0000-0001-5699-2676)
Institutions
- First Affiliated Hospital of Henan University of Science and Technology (CN)
Publication Details
- Journal
- PeerJ
- Published
- 2024-10-28
- DOI
- https://doi.org/10.7717/peerj.18362
- Citations
- 4
- Primary Topic
- Cancer Genomics and Diagnostics
- Type
- article
- Field-Weighted Citation Impact
- 1.14