The impact of voluntary wheel-running exercise on hippocampal neurogenesis and behaviours in response to nicotine cessation in rats

In summary, long-term wheel running positively affected the number of immature neurons in the hippocampus, which corresponded with an antidepressant response in nicotine-weaned rats. One possible mechanism underlying the positive effect of running on the affective state during nicotine cessation may be the reduction in deficits in DCX<sup>+</sup> cells in the hippocampus.

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Journal
Psychopharmacology
Published
2024-10-27
DOI
https://doi.org/10.1007/s00213-024-06705-7
Primary Topic
Neurogenesis and neuroplasticity mechanisms
Type
article
Field-Weighted Citation Impact
0.00

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article

The impact of voluntary wheel-running exercise on hippocampal neurogenesis and behaviours in response to nicotine cessation in rats

Dawid Gawliński, Łucja Balcerzak, Magdalena Zaniewska, Sabina Brygider et al.
Psychopharmacology
Neurogenesis and neuroplasticity mechanisms
article

The impact of voluntary wheel-running exercise on hippocampal neurogenesis and behaviours in response to nicotine cessation in rats

Dawid Gawliński, Łucja Balcerzak, Magdalena Zaniewska, Sabina Brygider, Iwona Majcher‐Maślanka, Urszula Głowacka, Sława Glińska
article en

Abstract

In summary, long-term wheel running positively affected the number of immature neurons in the hippocampus, which corresponded with an antidepressant response in nicotine-weaned rats. One possible mechanism underlying the positive effect of running on the affective state during nicotine cessation may be the reduction in deficits in DCX<sup>+</sup> cells in the hippocampus.

PsychopharmacologyVol. 241(12)
Jagiellonian University (PL), University of Łódź (PL), Maj Institute of Pharmacology (PL), Polish Academy of Sciences (PL)
Narodowe Centrum Nauki, Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk
Good health and well-being
Openalex Percentile: Top 77%
Neurogenesis and neuroplasticity mechanisms
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