CAR-Macrophage Therapy Alleviates Myocardial Ischemia-Reperfusion Injury

Our proof-of-concept study demonstrates the therapeutic potential of FAP CAR-Ms in alleviating myocardial I/R and potentially opens new avenues for the treatment of a range of heart diseases that include a fibrotic phenotype.

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Publication Details

Journal
Circulation Research
Published
2024-10-28
DOI
https://doi.org/10.1161/circresaha.124.325212
Citations
56
Primary Topic
Peptidase Inhibition and Analysis
Type
article
Field-Weighted Citation Impact
15.82
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article

CAR-Macrophage Therapy Alleviates Myocardial Ischemia-Reperfusion Injury

Jiahe Zhang, Jianghua Shen, Yang Zhao, Jiawan Wang et al.
56 citations
Circulation Research
Peptidase Inhibition and Analysis
15.82
article

CAR-Macrophage Therapy Alleviates Myocardial Ischemia-Reperfusion Injury

Jiahe Zhang, Jianghua Shen, Yang Zhao, Jiawan Wang, Yuan Hai-long, Moshi Song, Chuting He, Wanrun Xie, Shaolong Zhang, Zeya Li, Heng Du, Chaofan Yang, Jingdong Wu, Anhua Lei, Siqi Liu, Hao Zhang, Jin Zhang, Yujing Li, Xu Liu, Yanan Zhou, Pengfei Xu, Yihong Cai, Jinmiao Bi, Yingxin Liang, Yuhan Wang
article en
56 citations

Abstract

Our proof-of-concept study demonstrates the therapeutic potential of FAP CAR-Ms in alleviating myocardial I/R and potentially opens new avenues for the treatment of a range of heart diseases that include a fibrotic phenotype.

Circulation ResearchVol. 135(12)
Beijing Chao-Yang Hospital, Capital Medical University (CN), World Wide Web Consortium (US), Institute of Zoology (KZ), Zhejiang Radio and Television University (CN), Regenerative Medicine Institute (MX), Communication University of Zhejiang (CN), Center for Life Sciences (CN), Zhejiang Medicine (China) (CN), First Affiliated Hospital Zhejiang University (CN)
Good health and well-being
Openalex Percentile: Top 1%
Peptidase Inhibition and Analysis
15.82
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