Chemical Composition and Bioactivity Dataset Integration to Identify Antiproliferative Compounds in Phyllanthus Plants
These findings highlight the potential of <i>Phyllanthus</i> species as sources of novel anticancer agents, with specific arylnaphthalide lignans showing promising cytotoxic effects that could be further developed into therapeutic leads. Additionally, this study underscores the value of combining advanced analytical techniques with bioactivity testing to uncover bioactive compounds from natural sources. The results contribute to the growing body of evidence supporting the therapeutic relevance of <i>Phyllanthus</i> species and provide a foundation for future drug development efforts targeting cancer treatment.
Authors
- Ericsson Coy‐Barrera (ORCID: https://orcid.org/0000-0002-3553-9749)
- Taylor H. Díaz-Herrera (ORCID: https://orcid.org/0000-0002-1679-5560)
- Luis E. Díaz (ORCID: https://orcid.org/0000-0002-9588-9935)
Institutions
- Universidad de La Sabana (CO)
- Military University Nueva Granada (CO)
Publication Details
- Journal
- Pharmaceutics
- Published
- 2024-10-27
- DOI
- https://doi.org/10.3390/pharmaceutics16111381
- Citations
- 1
- Primary Topic
- Phytochemistry and Bioactivity Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.47
Funders
- Universidad de La Sabana
- Universidad Militar Nueva Granada