Chemical Composition and Bioactivity Dataset Integration to Identify Antiproliferative Compounds in Phyllanthus Plants

These findings highlight the potential of <i>Phyllanthus</i> species as sources of novel anticancer agents, with specific arylnaphthalide lignans showing promising cytotoxic effects that could be further developed into therapeutic leads. Additionally, this study underscores the value of combining advanced analytical techniques with bioactivity testing to uncover bioactive compounds from natural sources. The results contribute to the growing body of evidence supporting the therapeutic relevance of <i>Phyllanthus</i> species and provide a foundation for future drug development efforts targeting cancer treatment.

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Publication Details

Journal
Pharmaceutics
Published
2024-10-27
DOI
https://doi.org/10.3390/pharmaceutics16111381
Citations
1
Primary Topic
Phytochemistry and Bioactivity Studies
Type
article
Field-Weighted Citation Impact
0.47

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article

Chemical Composition and Bioactivity Dataset Integration to Identify Antiproliferative Compounds in Phyllanthus Plants

Ericsson Coy‐Barrera, Taylor H. Díaz-Herrera, Luis E. Díaz
1 citations
Pharmaceutics
Phytochemistry and Bioactivity Studies
0.47
article

Chemical Composition and Bioactivity Dataset Integration to Identify Antiproliferative Compounds in Phyllanthus Plants

Ericsson Coy‐Barrera, Taylor H. Díaz-Herrera, Luis E. Díaz
article en
1 citations

Abstract

These findings highlight the potential of <i>Phyllanthus</i> species as sources of novel anticancer agents, with specific arylnaphthalide lignans showing promising cytotoxic effects that could be further developed into therapeutic leads. Additionally, this study underscores the value of combining advanced analytical techniques with bioactivity testing to uncover bioactive compounds from natural sources. The results contribute to the growing body of evidence supporting the therapeutic relevance of <i>Phyllanthus</i> species and provide a foundation for future drug development efforts targeting cancer treatment.

PharmaceuticsVol. 16(11)
Universidad de La Sabana (CO), Military University Nueva Granada (CO)
Universidad de La Sabana, Universidad Militar Nueva Granada
Openalex Percentile: Top 33%
Phytochemistry and Bioactivity Studies
0.47
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