Unraveling the molecular mechanism of <scp>FgGcn5</scp> inhibition by phenazine‐1‐carboxamide: combined <scp><i>in silico</i></scp> and <scp><i>in vitro</i></scp> studies
In summary, our study sheds light on the mechanism by which PCN inhibits the acetylation function of FgGcn5, providing a foundation for the development of drugs or fungicides targeting histone acetyltransferases. © 2024 Society of Chemical Industry.
Authors
- Jingjing Guo (ORCID: https://orcid.org/0000-0002-4632-4364)
- S. Yang (ORCID: https://orcid.org/0000-0002-0204-984X)
- Yuguang Mu (ORCID: https://orcid.org/0000-0002-2499-026X)
- Feng Zhang (ORCID: https://orcid.org/0000-0002-3200-5506)
- Qing Luo (ORCID: https://orcid.org/0000-0002-0418-1553)
- Hancheng Wang (ORCID: https://orcid.org/0000-0001-7423-7121)
- Lei Li (ORCID: https://orcid.org/0009-0005-1386-5382)
Institutions
- Nanjing Agricultural University (CN)
- Nanyang Technological University (SG)
- China Tobacco (CN)
- Tobacco Research Institute (CN)
- Macao Polytechnic University (MO)
Publication Details
- Journal
- Pest Management Science
- Published
- 2024-10-28
- DOI
- https://doi.org/10.1002/ps.8496
- Citations
- 2
- Primary Topic
- Peptidase Inhibition and Analysis
- Type
- article
- Field-Weighted Citation Impact
- 0.57
Funders
- National Key Research and Development Program of China