Causal relationship between cancer and immune cell traits: A two-sample mendelian randomization study
Our MR study suggests a potential relationship between immune traits and cancers, particularly highlighting 14 immune traits that are simultaneously influenced by two or three of five cancer types, while also indicating that 6 immune traits may simultaneously contribute to the development of two of the cancers. This elucidation enables us to reveal a significant involvement of immune traits in cancer progression, providing critical insights into how immune traits affect cancer susceptibility.
Authors
- Qinsong Sheng
- Jingjing Fan (ORCID: https://orcid.org/0000-0002-1110-5735)
- Lijun Jin (ORCID: https://orcid.org/0000-0002-8684-1120)
- Zuyi Yang (ORCID: https://orcid.org/0000-0002-6471-6783)
- Zejing Qiu
- Xingxing Huang
- Jun He
Institutions
- Hangzhou Normal University (CN)
- Affiliated Hospital of Hangzhou Normal University (CN)
- Hangzhou Hospital of Traditional Chinese Medicine (CN)
- People's Hospital of Wangcheng District Changsha
- Zhejiang University (CN)
Publication Details
- Journal
- Heliyon
- Published
- 2024-10-28
- DOI
- https://doi.org/10.1016/j.heliyon.2024.e39732
- Citations
- 2
- Primary Topic
- Genetic Associations and Epidemiology
- Type
- article
- Field-Weighted Citation Impact
- 1.10