Validation of Inter-Reader Agreement/Consistency for Quantification of Ellipsoid Zone Integrity and Sub-RPE Compartmental Features Across Retinal Diseases
Analyses demonstrated high reliability and consistency of segmentation of outer retinal compartmental features using a completely human/manual approach or a semi-automated approach to segmentation. These results support the critical role that measuring features, such as photoreceptor preservation through EZ integrity, in future clinical trials may optimize clinical care.
Authors
- Jordan R. Bell (ORCID: https://orcid.org/0000-0001-7463-2973)
- Jon Whitney (ORCID: https://orcid.org/0000-0003-2637-752X)
- Nicole Cardwell
- Thuy Le (ORCID: https://orcid.org/0000-0002-2528-1692)
- Hasan Cetin (ORCID: https://orcid.org/0000-0001-9492-4957)
- Justis P. Ehlers (ORCID: https://orcid.org/0000-0001-6763-7768)
- Sunil K. Srivasatava
Institutions
- Cleveland Clinic (US)
- Cleveland Clinic Lerner College of Medicine (US)
- Advanced Imaging Research (United States) (US)
- Cleveland Eye Clinic (US)
- Case Western Reserve University (US)
- Center for Excellence in Education (US)
Publication Details
- Journal
- Diagnostics
- Published
- 2024-10-27
- DOI
- https://doi.org/10.3390/diagnostics14212395
- Citations
- 3
- Primary Topic
- Retinal Imaging and Analysis
- Type
- article
- Field-Weighted Citation Impact
- 1.21
Funders
- Cleveland Clinic