Impact of obesity on pathological complete remission in early stage breast cancer patients after neoadjuvant chemotherapy: a retrospective study from a German University breast center
In this retrospective study, obesity significantly affected the likelihood of achieving pCR in patients with eBC cancer undergoing NACT after adjusting for covariates. While obesity is a known risk factor for breast cancer development and progression, its impact on the efficacy of NACT in terms of achieving pCR was positive in our study. These findings contribute to the ongoing debate in the literature, though the retrospective design and potential uncontrolled factors should be considered.
Authors
- Dominik Dannehl (ORCID: https://orcid.org/0000-0002-7653-8283)
- Sara Y. Brucker (ORCID: https://orcid.org/0000-0001-5162-1542)
- Léa Louise Volmer
- Andreas Hartkopf
- D. Wallwiener (ORCID: https://orcid.org/0000-0002-4635-5283)
- Alexander Englisch
- Tobias Engler (ORCID: https://orcid.org/0000-0002-8063-2053)
- Sabine Matovina (ORCID: https://orcid.org/0000-0001-5864-0244)
- Christian M. Tegeler (ORCID: https://orcid.org/0000-0001-6688-7351)
- Johannes Felix Englisch (ORCID: https://orcid.org/0009-0005-5061-2042)
- Kenneth Eissler
Institutions
- University of Tübingen (DE)
Publication Details
- Journal
- Archives of Gynecology and Obstetrics
- Published
- 2024-10-28
- DOI
- https://doi.org/10.1007/s00404-024-07786-7
- Citations
- 3
- Primary Topic
- Cancer Risks and Factors
- Type
- article
- Field-Weighted Citation Impact
- 0.85
Funders
- Universitätsklinikum Tübingen