Specific and Polyfunctional T Cell Response Against N-Methyl-d-aspartate Receptor in an Autoantibody-Mediated Encephalitis Model

This study identified, for the first time, a potential contribution of T helper cells in the pathology of NMDAR AE and paved the way for the development of future tolerogenic approaches to treat relapses.

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Publication Details

Journal
Biomedicines
Published
2024-10-25
DOI
https://doi.org/10.3390/biomedicines12112458
Primary Topic
Autoimmune Neurological Disorders and Treatments
Type
article
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article

Specific and Polyfunctional T Cell Response Against N-Methyl-d-aspartate Receptor in an Autoantibody-Mediated Encephalitis Model

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article

Specific and Polyfunctional T Cell Response Against N-Methyl-d-aspartate Receptor in an Autoantibody-Mediated Encephalitis Model

Olivier Toutirais, Jérôme Leprince, Denis Vivien, Benoı̂t Bernay, Léonie Lesec, Benjamin Lefranc, Jonathane Furon, Célia Seillier, Julien Serrier, Caroline Regnauld, Brigitte Le Mauff, Fabián Docagne
article en

Abstract

This study identified, for the first time, a potential contribution of T helper cells in the pathology of NMDAR AE and paved the way for the development of future tolerogenic approaches to treat relapses.

BiomedicinesVol. 12(11)
Inserm (FR), Normandie Université (FR), Cyceron (FR), Physiopathologie et imagerie des troubles neurologiques, Université de Rouen Normandie (FR), Université de Caen Normandie (FR)
Good health and well-being
Openalex Percentile: Top 70%
Autoimmune Neurological Disorders and Treatments
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