Epidemiology and Treatment Trends in the Management of Dupuytren's Disease From 2016 to 2022

Background The United States has been experiencing rapid demographic changes in recent years; therefore, it is crucial to understand how these changes affect the diagnosis and treatment of Dupuytren disease to provide high-quality patient care. This study examines the demographics of Dupuytren disease and its surgical management. Methods International Classification of Disease-10 (ICD-10) diagnostic codes were used to query the TriNetX database for all patients diagnosed with Dupuytren disease from 2016 to 2022. Current procedure terminology (CPT) codes were used to stratify the method of surgical interventions for Dupuytren disease and to form patient cohorts. Results The incidence of patients diagnosed with Dupuytren disease in the United States from 2016 to 2022 showed a steady annual increase in cases, peaking at 22,711 in 2022 compared to 11,271 in 2016. Most diagnoses occurred in patients aged 65-90 years, accounting for 72% of patients. Dupuytren disease was more prevalent in males (M/F ratio of 1.5/1) and White patients. Notable comorbidities included diabetes in 25% of patients, smoking history in 11% of patients, and hypothyroidism in 17% of patients. Patients with a smoking history had higher rates of surgical intervention, while those with hyperthyroidism had the highest rates of palmar fasciotomies. Males had higher rates of surgical intervention of all types compared to females. Overall, the highest surgical intervention rate was for partial fasciectomy, with single-digit release used in 9.9% of patients, and the lowest for palmar fasciotomy, used only in 1.4% of patients. Conclusion This study showed that the rates of Dupuytren disease are rapidly increasing in the United States. Additionally, there are significant differences in the diagnosis and treatment of Dupuytren disease based on patient demographics. Understanding these differences provides an opportunity to explore ways to tailor treatment and allocate resources to best meet patients' needs and improve the quality of care they receive.