RIFM fragrance ingredient safety assessment, 2-butyl-4,4,6-trimethyl-1,3-dioxane, CAS registry number 54546-26-8
• 2-Butyl-4,4,6-trimethyl-1,3-dioxane; a safety assessment based on RIFM's criteria. • A safety assessment based on 7 human health endpoints plus environmental. • All endpoints were cleared using target data, read-across, and/or TTC.
Authors
- D. Botelho
- I.G. Sipes
- A.M. Api (ORCID: https://orcid.org/0000-0002-8960-6521)
- W. Dekant (ORCID: https://orcid.org/0000-0002-6292-6138)
- H. Chon
- G. Sullivan (ORCID: https://orcid.org/0000-0001-7007-0926)
- N. Sadekar (ORCID: https://orcid.org/0000-0002-8329-3720)
- A. Lapczynski
- D. Belsito (ORCID: https://orcid.org/0000-0003-1229-6673)
- M.L. Dagli (ORCID: https://orcid.org/0000-0001-7031-6711)
- Y. Tokura (ORCID: https://orcid.org/0000-0001-7452-6919)
- L. Jones (ORCID: https://orcid.org/0000-0002-8706-2014)
- M. Bruze (ORCID: https://orcid.org/0000-0002-2919-3227)
- G. Ritacco
- C. Deodhar (ORCID: https://orcid.org/0000-0002-3906-9940)
- H. Moustakas (ORCID: https://orcid.org/0000-0003-2895-1695)
- T.M. Penning (ORCID: https://orcid.org/0000-0002-3937-1066)
- M. Lavelle
- A.D. Fryer (ORCID: https://orcid.org/0000-0003-1712-9831)
- I. Lee
- G.A. Burton (ORCID: https://orcid.org/0000-0002-8660-6294)
- I Schember
- A. Bryant-Freidrich
- K. Joshi
- Y. Thakkar
- T.W. Schultz (ORCID: https://orcid.org/0000-0002-9788-1662)
- F. Siddiqi
- J Muldoon (ORCID: https://orcid.org/0009-0006-3558-6293)
- M.A. Cancellieri
- K Farrell
- A Bartlett
Institutions
- University of Arizona (US)
- Oregon Health & Science University (US)
- Universidade de São Paulo (BR)
- Wayne State University (US)
- Lund University (SE)
- University of Würzburg (DE)
- University of Michigan (US)
- Columbia University Irving Medical Center (US)
- Research Institute for Fragrance Materials (US)
- Hamamatsu University School of Medicine (JP)
- University of Tennessee at Knoxville (US)
- University of Pennsylvania (US)
Publication Details
- Journal
- Food and Chemical Toxicology
- Published
- 2024-10-28
- DOI
- https://doi.org/10.1016/j.fct.2024.115072
- Primary Topic
- Contact Dermatitis and Allergies
- Type
- article
- Field-Weighted Citation Impact
- 0.00