RIFM fragrance ingredient safety assessment, 2-butyl-4,4,6-trimethyl-1,3-dioxane, CAS registry number 54546-26-8

• 2-Butyl-4,4,6-trimethyl-1,3-dioxane; a safety assessment based on RIFM's criteria. • A safety assessment based on 7 human health endpoints plus environmental. • All endpoints were cleared using target data, read-across, and/or TTC.

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Publication Details

Journal
Food and Chemical Toxicology
Published
2024-10-28
DOI
https://doi.org/10.1016/j.fct.2024.115072
Primary Topic
Contact Dermatitis and Allergies
Type
article
Field-Weighted Citation Impact
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article

RIFM fragrance ingredient safety assessment, 2-butyl-4,4,6-trimethyl-1,3-dioxane, CAS registry number 54546-26-8

D. Botelho, I.G. Sipes, A.M. Api, W. Dekant et al.
Food and Chemical Toxicology
Contact Dermatitis and Allergies
article

RIFM fragrance ingredient safety assessment, 2-butyl-4,4,6-trimethyl-1,3-dioxane, CAS registry number 54546-26-8

D. Botelho, I.G. Sipes, A.M. Api, W. Dekant, H. Chon, G. Sullivan, N. Sadekar, A. Lapczynski, D. Belsito, M.L. Dagli, Y. Tokura, L. Jones, M. Bruze, G. Ritacco, C. Deodhar, H. Moustakas, T.M. Penning, M. Lavelle, A.D. Fryer, I. Lee, G.A. Burton, I Schember, A. Bryant-Freidrich, K. Joshi, Y. Thakkar, T.W. Schultz, F. Siddiqi, J Muldoon, M.A. Cancellieri, K Farrell, A Bartlett
article en

Abstract

• 2-Butyl-4,4,6-trimethyl-1,3-dioxane; a safety assessment based on RIFM's criteria. • A safety assessment based on 7 human health endpoints plus environmental. • All endpoints were cleared using target data, read-across, and/or TTC.

Food and Chemical ToxicologyVol. 194
University of Arizona (US), Oregon Health & Science University (US), Universidade de São Paulo (BR), Wayne State University (US), Lund University (SE), University of Würzburg (DE), University of Michigan (US), Columbia University Irving Medical Center (US), Research Institute for Fragrance Materials (US), Hamamatsu University School of Medicine (JP), University of Tennessee at Knoxville (US), University of Pennsylvania (US)
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Openalex Percentile: Top 60%
Contact Dermatitis and Allergies
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