IL-33 Induces a Switch in Intestinal Metabolites Revealing the Tryptophan Pathway as a Target for Inducing Allograft Survival
Our study reveals a new property for IL-33 as a modulator of the intestinal microbiota and metabolites, especially those involved with Trp metabolism. In addition, we demonstrate that KA favors Tregs in vivo, positively affecting skin transplantation survival.
Authors
- Karina Pino‐Lagos (ORCID: https://orcid.org/0000-0002-4070-6169)
- Camila Pinto (ORCID: https://orcid.org/0000-0001-9386-9407)
- Federico Cifuentes (ORCID: https://orcid.org/0000-0003-0266-8189)
- Felipe Gálvez‐Jirón
- Javiera De Solminihac
- Tomás Carrasco-Loncharic
- Eduardo González-Mienert
Institutions
- Pontificia Universidad Católica de Chile (CL)
- Universidad de Los Andes, Chile (CL)
Publication Details
- Journal
- Nutrients
- Published
- 2024-10-27
- DOI
- https://doi.org/10.3390/nu16213655
- Citations
- 1
- Primary Topic
- IL-33, ST2, and ILC Pathways
- Type
- article
- Field-Weighted Citation Impact
- 0.24
Funders
- Dartmouth College