Ultrastructural investigation of the posterior hyaloid membrane in posterior vitreous detachment
PHM isolated from eyes with PVD is distinct from artefactual separation of the ILM from the retina during dissection. PHM is ultrastructurally distinct from vitreous gel and is a separate entity. The en face appearance of PHM is similar to that of ILM, suggesting that in PVD, PHM forms from separation of an inner layer of ILM. Laminocytes may play a role in the pathogenesis of vitreoretinal disease.
Authors
- Matthew A. Hayes (ORCID: https://orcid.org/0000-0002-2127-898X)
- Martin P. Snead (ORCID: https://orcid.org/0000-0003-0042-8659)
- Thomas Nixon (ORCID: https://orcid.org/0000-0003-2790-1135)
- David Snead (ORCID: https://orcid.org/0000-0002-0766-9650)
Institutions
- MRC Cognition and Brain Sciences Unit (GB)
- University of Cambridge (GB)
- University Hospitals Coventry and Warwickshire NHS Trust (GB)
- Addenbrooke's Hospital (GB)
- University College London (GB)
Publication Details
- Journal
- Eye
- Published
- 2024-10-28
- DOI
- https://doi.org/10.1038/s41433-024-03407-4
- Primary Topic
- Retinal and Macular Surgery
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- University of Cambridge
- Cambridge University Hospitals