Pharmacogenomic Study of Selected Genes Affecting Amlodipine Blood Pressure Response in Patients with Hypertension
Our finding suggests that the SNPs rs2239050/CACNA1C, rs312481/CACNA1D and rs429/ACE influence amlodipine blood pressure response in patients with hypertension. It is recommended that prior knowledge of amlodipine associated pharmacogenetic variants is important that could improve its treatment outcomes in hypertensive patients.
Authors
- Muhammad Saeed (ORCID: https://orcid.org/0000-0002-5426-1009)
- Asif Jan (ORCID: https://orcid.org/0000-0003-3880-5579)
- Tahir Muhammad (ORCID: https://orcid.org/0000-0001-5819-1397)
- Syed Shaukat Ali
- Jun-Ya Kaimori (ORCID: https://orcid.org/0000-0001-6690-5804)
- Abdullah R. Alanzi (ORCID: https://orcid.org/0009-0000-2565-6573)
- Ramzi A. Mothana (ORCID: https://orcid.org/0000-0003-4220-7854)
- Rani Akbar
- Mehtab Khan
Institutions
- Centre for Addiction and Mental Health (CA)
- Université de Moncton (CA)
- Abdul Wali Khan University Mardan (PK)
- University of Toronto (CA)
- King Saud University (SA)
- University of Peshawar (PK)
- Qurtuba University of Science and Information Technology (PK)
- Chard & District Hospital (GB)
- University of Malakand (PK)
- University of Engineering and Technology Peshawar (PK)
- The University of Osaka (JP)
Publication Details
- Journal
- Pharmacogenomics and Personalized Medicine
- Published
- 2024-10-01
- DOI
- https://doi.org/10.2147/pgpm.s481068
- Citations
- 3
- Primary Topic
- Blood Pressure and Hypertension Studies
- Type
- article
- Field-Weighted Citation Impact
- 1.21
Funders
- King Saud University