A New Objective Diagnostic Tool for Attention-Deficit Hyper-Activity Disorder (ADHD): Development of the Distractor-Embedded Auditory Continuous Performance Test
<b>Background/Objectives</b>: Attention-Deficit Hyperactivity Disorder (ADHD) is a prevalent neurodevelopmental disorder characterized by inattention, hyperactivity, and impulsivity. Traditional diagnostic methods, which depend on subjective assessments, often lack precision. This study evaluates the validity and reliability of a newly developed diagnostic tool, the Distractor-Embedded Auditory Continuous Performance Test (da-CPT), which integrates auditory stimuli with distractors to enhance the clinical utility of ADHD diagnosis. <b>Methods</b>: The study included 160 children aged 6-12 years, comprising 80 with a confirmed ADHD diagnosis and 80 controls. All participants completed the da-CPT, a web-based tool designed to assess inattention, hyperactivity, impulsivity, and timing via an auditory-based task. To validate the da-CPT, participants also completed the Conners' Parent Rating Scale-Revised Short Form (CPRS-R) and either the MOXO or IVA-2 tests. Data were analyzed using ROC curves and statistical correlations to assess sensitivity, specificity, and overall diagnostic accuracy. <b>Results</b>: The da-CPT demonstrated high diagnostic accuracy, with a sensitivity of 91.25% and specificity of 83.75%. ROC analysis indicated that the inattention index had the highest discriminatory power (AUC = 0.881), followed by timing, impulsivity, and hyperactivity (all <i>p</i> < 0.01). Furthermore, the da-CPT scores were strongly correlated with ADHD severity (<i>p</i> < 0.01). <b>Conclusions</b>: This study confirms that the da-CPT is a valid and reliable tool for diagnosing ADHD in children aged 6-12. By incorporating auditory stimuli and distractors, the tool offers a more ecologically valid assessment of ADHD symptoms in clinical settings, improving diagnostic precision and utility.
Authors
- Hacer Karacan (ORCID: https://orcid.org/0000-0001-6788-008X)
- Mehmet Cengiz (ORCID: https://orcid.org/0000-0003-4972-167X)
- Barış Karacan
- Ahmet Özaslan (ORCID: https://orcid.org/0000-0001-7741-201X)
- Elvan İşeri (ORCID: https://orcid.org/0000-0002-1809-5867)
- Esra Güney (ORCID: https://orcid.org/0000-0002-4043-8301)
- Esin Gökçe Sarıpınar
- Mehmet Sevri (ORCID: https://orcid.org/0000-0002-1551-9476)
- Asiye Uğraş Dikmen
Institutions
- Recep Tayyip Erdoğan University (TR)
- University of Illinois Chicago (US)
- Gülhane Askerî Tıp Akademisi (TR)
- Gazi University (TR)
Publication Details
- Journal
- Journal of Clinical Medicine
- Published
- 2024-10-27
- DOI
- https://doi.org/10.3390/jcm13216438
- Citations
- 3
- Primary Topic
- Attention Deficit Hyperactivity Disorder
- Type
- article
- Field-Weighted Citation Impact
- 1.16