Extensive DNA Damage and Loss of Cell Viability Occur Synergistically With the Combination of Recombinant Methioninase and Paclitaxel on Pancreatic Cancer Cells which Report DNA-Damage Response in Real Time
The present study suggests the synergy of methionine restriction and chemotherapy is due, at least in part, to DNA damage of cancer cells.
Authors
- Michael Bouvet (ORCID: https://orcid.org/0000-0002-0086-2159)
- Shinji Miwa (ORCID: https://orcid.org/0000-0002-5962-8287)
- Byung Mo Kang (ORCID: https://orcid.org/0000-0003-0900-094X)
- Katsuhiro Hayashi (ORCID: https://orcid.org/0000-0001-8665-2154)
- Norio Yamamoto (ORCID: https://orcid.org/0000-0002-7250-625X)
- Robert M. Hoffman (ORCID: https://orcid.org/0000-0002-0049-0041)
- MOTOKAZU SATO
- Takashi Higuchi (ORCID: https://orcid.org/0000-0003-2896-4939)
- Hiroyuki Tsuchiya (ORCID: https://orcid.org/0000-0003-0730-7921)
- KOHEI MIZUTA
- Satoru Demura
- HIROAKI KIMURA
- Kentaro Igarashi (ORCID: https://orcid.org/0000-0003-2278-1736)
- Sei Morinaga (ORCID: https://orcid.org/0000-0003-2961-9432)
- Qinghong Han
Institutions
- Kanazawa University (JP)
- University of California San Diego (US)
- AntiCancer (United States) (US)
Publication Details
- Journal
- Cancer Genomics & Proteomics
- Published
- 2024-10-28
- DOI
- https://doi.org/10.21873/cgp.20475
- Citations
- 1
- Primary Topic
- Cancer Research and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.39