Factors Associated with Adherence to Antihypertensive Treatment and Complications Due to Inadequate Adherence in Patients Undergoing Hemodialysis at the Hospital Regional Puebla ISSSTE

Background: Poor medication adherence hampers hypertension control and increases the risk of adverse health outcomes. Medication adherence can be measured with direct and indirect methods.In México not exist any study to evaluate the medication adherence in patiens under hemodialysis.For this is important to assess Mexican hypertensive patients’ adherence rate to hypertension therapeutic regimen and to identify the strongest predictors of adherence rate among such patients. Methods: A descriptive comparison design and convenience sampling were used. The sample comprised 113 participants who came to their regular sessions at hemodialysis in a ISSSTE hospital. The Hill-Bone Compliance to High Blood Pressure Therapy Scale indirectly assesses adherence to hypertension therapy in three behavioral domains: appointment keeping, diet and medication adherence. Secondary objectives to evaluate if there is a relationship between adherence to treatment and years on hemodialysis, levels of urea, potassium, creatinine, albumin and ferritin. Results: 113 patients were evaluated, of which 54 were women and 59 men.The length of stay on hemodialysis was from 1 to 12 years. 89.4% have been on hemodialysis for less than 6 years.85.8% of patients obtained a good adherence result.14.2% of patients have moderate-poor adherence to antihypertensive treatment.We found that albumin levels above 3.5 g/dl were correlated with better adherence to pharmacological treatment (p ≤.0405).During the time of patient evaluation, 5 deaths were reported, all belonging to the group with poor adherence to pharmacological treatment. Conclusion: This is the first study to be include hemodialysis patients in Mexico.Adherence to taking antihypertensive medications was good overall among the study participants; these participants, however, they agreed to have a high consumption of table salt and forget to take their medication at least once a week.The HBCHBPT Scale has high versatility globally and has been used in various settings by various healthcare worker cadres and researchers.The scale has several strengths, including high adherence phenotyping capabilities, contributing to the paradigm shift toward personalized health care, Funding: Government Support – Non-U.S.