Innovation in Dialysis: Air Trap Level Management

Background: Millions with end-stage kidney disease rely on hemodialysis, making the safety of dialysis devices crucial. Air traps in these devices prevent air embolism by removing air bubbles. However, traditional air traps often fail to remove all air, detect microbubbles, or operate autonomously thus increasing the risk for care disruptions and complications. Methods: The Moda-flx Hemodialysis System™ uses a dual mechanism to manage air infusion. The primary system includes an air trap/drip chamber with a level control system. Additionally, a venous air sensor detects air downstream of the air trap. This design ensures introduced air is vented or detected before reaching the patient. Testing scenarios use Dialin to simulate air bubbles in various operational modes. System performance and fault conditions are evaluated at low, moderate, and high rates of continuous air infusion. See Figure 1. Results: At low air infusion rates, the system vents excess air, preventing air from entering the venous line. At moderate rates, if the blood level in the air trap doesn’t recover quickly, the system triggers an alarm, stops the blood pump, and clamps the venous line. At high rates, rapid blood level drops prevent quick venting, allowing air into the venous line. The system triggers an alarm, stops the blood pump, clamps the venous line, and activates dialysate bypass. Comprehensive testing confirms Moda-flx effectively manages air infusion at all rates. Conclusion: The Moda-flx Hemodialysis System™ introduces an innovative approach to air trap management, significantly enhancing patient safety in dialysis treatments. The primary air trap level control system maintains optimal blood levels within the air trap and is complemented by a secondary venous air bubble detection system, ensuring comprehensive risk mitigation. This dual mechanism represents advancements in dialysis device design, ensuring reliable protection in all conditions. Funding: Commercial Support - Diality