Haptoglobin polymorphism, vitamin E and mortality: the Ludwigshafen Risk and Cardiovascular Health Study
Particularly in patients with diabetes mellitus we could show a significant interaction of γ-tocopherol plasma concentration and HP genotype. Carriers of the Hp2-2 genotype seemed to benefit from higher plasma concentrations of γ-tocopherol. Further research is warranted to elucidate the underlying mechanisms and potential therapeutic implications in cardiovascular disease management.
Authors
- Graciela Delgado (ORCID: https://orcid.org/0000-0002-1272-7210)
- Thomas Dschietzig (ORCID: https://orcid.org/0000-0003-1186-8713)
- Marcus E. Kleber (ORCID: https://orcid.org/0000-0003-0663-7275)
- Tanja Langsenlehner
- Wilfried Renner (ORCID: https://orcid.org/0000-0002-6199-4382)
- Angela P. Moissl (ORCID: https://orcid.org/0000-0003-0302-2136)
- Bernhard Krämer
- Brigitte M. Winklhofer‐Roob
- Franz Paul Armbruster
- Winfried März
Institutions
- University of Graz (AT)
- Medical University of Graz (AT)
- Heidelberg University (DE)
- University Hospital Heidelberg (DE)
- Synlab (Germany) (DE)
- University Medical Centre Mannheim (DE)
Publication Details
- Journal
- BMJ Nutrition Prevention & Health
- Published
- 2024-10-28
- DOI
- https://doi.org/10.1136/bmjnph-2024-001061
- Citations
- 1
- Primary Topic
- Hemoglobin structure and function
- Type
- article
- Field-Weighted Citation Impact
- 0.33