Predictive Factors of Catheter-Related Bloodstream Infection among Patients on Hemodialysis

Background: Catheter-related bloodstream infection (CRBSI) is a one of the major cause of morbidity and mortality among end stage renal disease patients undergoing hemodialysis using central venous catheter (CVC). The study aimed to investigate the predictors of catheter-related bloodstream infections (CRBSI) with end-stage renal disease (ESRD) patients on hemodialysis through a central venous catheter. Methods: We conducted a retrospective analytical study to investigate the predictive factors and associated outcome of CRBSI among ESRD patients undergoing hemodialysis at Cotabato Regional and Medical Center. A total of 42 patients who have central venous access(CVC) were included in this study from January 1, 2020 to December 31, 2022. We obtained the patient's demographic data, laboratory results at admission, information regarding catheter infections, culture results, and other information from electronic medical records. Results: The study involved patients with a mean age of 48±15 years, with more females (59.5%, 25 patients) than males (40.5%, 17 patients). The primary causes of hemodialysis were diabetes mellitus (38.1%) and hypertension (35.7%), which were also the most common co-morbidities. Non-tunneled catheters were the majority of the central venous access used in the study. Sepsis is a significantly associated outcome of CRBSI among hemodialysis using central venous catheter with p value of 0.05. According to logistic regression analysis, the development of CRBSI was predicted by ages greater than 71 with a p-value of 0.023. Conclusion: We conclude that ESRD patients undergoing hemodialysis with venous catheters, who are 71 years of age or older, are at an increased risk of developing CRBSI and sepsis is a significantly associated outcome.