Refined Management of Serum Potassium Is Necessary in Patients on Peritoneal Dialysis

Background: Chronic renal failure is a high risk factor for hyperkalemia but is generally considered to be rare in peritoneal dialysis patients. Methods: 86 patients with peritoneal dialysis who were followed up regularly every month in the outpatient clinic from January 2022 to February 2023 were selected as the research subjects and followed up for one year. Collect general data such as gender, age, dialysis age, primary disease, weight, blood pressure, urine output, etc. Dialysis data: peritoneal dialysis method, whether the abdomen is persistent, treatment volume, ultrafiltration volume, Kt/v, Ccr, etc; biochemical indicators : Hemoglobin, parathyroid hormone, NT-proBNP, albumin, blood sugar, calcium, phosphorus, potassium, sodium, chlorine, carbon dioxide, etc. Results: 1. There were 48 patients with CAPD and 38 patients with APD. There were no statistics on weight, age, kt/v, diastolic blood pressure, hemoglobin, parathyroid hormone, BNP, albumin, blood sugar, calcium, potassium, chloride, and carbon dioxide between the two groups (Tab1). 2. The incidence of hyperkalemia was 12.98%, if the threshold for diagnosing hyperkalemia defined as K>5.0 mmol/l (2.33% K≥5.5mmol/L) (Fig1). 62.5% of patients with hyperkalemia relapse within one year (Fig2). 3. There were 50 patients dwell abdomen. The occurrence of hyperkalemia was related to dry abdomen (P=0.031). (Tab2) Conclusion: The study found that peritoneal dialysis patients are also a high-risk group for hyperkalemia, especially those with poor residual renal function or dry abdomen. The threshold for diagnosing hyperkalemia defined as K>5.0 mmol/l, which significantly improves the diagnostic efficiency of hyperkalemia. We can detect the risk of hyperkalemia early, avoid recurrence of hyperkalemia, and reduce the risk of cardiovascular mortality in patients with peritoneal dialysis.