Management and outcomes in pulmonary arterial hypertension patients with sepsis
Patients with PAH and sepsis have high mortality and receive different treatments than controls, with more reliance on vasopressors and less on fluid resuscitation. PAH patients who received less fluids had higher mortality and those who received no fluids had a longer time to receiving antibiotics, indicating a potential delay in recognizing sepsis. Timely recognition of sepsis and dynamic decision-making around fluid resuscitation remains critical in this high-risk population.
Authors
- Spencer Flynn (ORCID: https://orcid.org/0000-0001-5854-3751)
- Alexander E. Sherman (ORCID: https://orcid.org/0000-0002-5622-2804)
- Haidee Chen (ORCID: https://orcid.org/0000-0003-2723-9313)
- Rajan Saggar (ORCID: https://orcid.org/0000-0002-5536-5934)
- Richard N. Channick (ORCID: https://orcid.org/0000-0002-9016-4468)
- Russell Kerbel (ORCID: https://orcid.org/0000-0003-4768-3235)
- Sonia Jasuja (ORCID: https://orcid.org/0009-0003-2759-4128)
- Summer Gupta
Institutions
- University of California, Los Angeles (US)
- UCLA Medical Center (US)
Publication Details
- Journal
- BMC Pulmonary Medicine
- Published
- 2024-10-28
- DOI
- https://doi.org/10.1186/s12890-024-03355-5
- Citations
- 2
- Primary Topic
- Pulmonary Hypertension Research and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.84