Clinical significance of Talin-1 and HER-2 status in different types of gastric carcinoma
Higher cytoplasmic Talin-1 expression is associated with less invasive tumor behavior, while increased membranous HER-2 expression is associated with metastasis in SRC-type GC. These findings suggest potential use in assessing diagnosis and screening high-risk cancer patients, particularly those with SRC-type GC.
Authors
- Masoumeh Dehghan Manshadi
- Zahra Madjd (ORCID: https://orcid.org/0000-0001-7329-2583)
- Fatemeh Tajik (ORCID: https://orcid.org/0000-0001-9764-2947)
- Fahimeh Fattahi (ORCID: https://orcid.org/0000-0002-2563-0004)
- Pegah Babaheidarian (ORCID: https://orcid.org/0000-0001-9488-7228)
- Roya Ghods (ORCID: https://orcid.org/0000-0001-5996-3758)
- Leili Saeednejad Zanjani (ORCID: https://orcid.org/0000-0002-5035-3766)
- Farideh Hashemi (ORCID: https://orcid.org/0000-0002-4865-3727)
- Sadegh Safaei
Institutions
- Arak University of Medical Sciences (IR)
- Iran University of Medical Sciences (IR)
Publication Details
- Journal
- Biomarkers
- Published
- 2024-10-28
- DOI
- https://doi.org/10.1080/1354750x.2024.2423270
- Citations
- 2
- Primary Topic
- Cell Adhesion Molecules Research
- Type
- article
- Field-Weighted Citation Impact
- 0.77
Funders
- Iran University of Medical Sciences