Evaluation of toxicity of feed additive for highly productive animals

The study of new feed additives requires toxicological research to assess their safety for further use. This research presents the results of an acute toxicity study of the feed additive “Bodrivin,” developed for highly productive animals of dairy, meat-dairy, and meat breeds. The aim is to prevent stress of various etiologies, enhance the nutritional value of the diet, especially during periods of energy deficiency, and consequently improve productivity and profitability in production. Non-linear laboratory rats were used for the experiment. The first experimental group received a single oral dose of the feed additive via syringe and atraumatic needle with a bulbous end at a dosage of 2000 mg/kg. After obtaining the results of the experiment over a 14-day period, a similar experiment was conducted on the second experimental group. At the conclusion of the experiment, no signs indicating toxic effects of the studied feed additive were observed in the animals, and the body weight of the experimental animals remained unchanged in both the first and second series of the experiment. The acute toxicity study of the feed additive “Bodrivin” indicated that the evaluated feed additive belongs to Class V of danger according to GOST 32644-2014.

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Publication Details

Journal
Pharmacy Formulas
Published
2024-10-28
DOI
https://doi.org/10.17816/phf639873
Primary Topic
Animal Nutrition and Physiology
Type
article
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article

Evaluation of toxicity of feed additive for highly productive animals

Irina V. Lunegova, A. M. Lunegov, Alexander A. Svyatkovsky
Pharmacy Formulas
Animal Nutrition and Physiology
article

Evaluation of toxicity of feed additive for highly productive animals

Irina V. Lunegova, A. M. Lunegov, Alexander A. Svyatkovsky
article en

Abstract

The study of new feed additives requires toxicological research to assess their safety for further use. This research presents the results of an acute toxicity study of the feed additive “Bodrivin,” developed for highly productive animals of dairy, meat-dairy, and meat breeds. The aim is to prevent stress of various etiologies, enhance the nutritional value of the diet, especially during periods of energy deficiency, and consequently improve productivity and profitability in production. Non-linear laboratory rats were used for the experiment. The first experimental group received a single oral dose of the feed additive via syringe and atraumatic needle with a bulbous end at a dosage of 2000 mg/kg. After obtaining the results of the experiment over a 14-day period, a similar experiment was conducted on the second experimental group. At the conclusion of the experiment, no signs indicating toxic effects of the studied feed additive were observed in the animals, and the body weight of the experimental animals remained unchanged in both the first and second series of the experiment. The acute toxicity study of the feed additive “Bodrivin” indicated that the evaluated feed additive belongs to Class V of danger according to GOST 32644-2014.

Pharmacy FormulasVol. 6(3)
St Petersburg University (RU), Ministry of Health of the Russian Federation (RU), University of Veterinary Medicine (HU), Saint Petersburg State University of Veterinary Medicine (RU)
Openalex Percentile: Top 79%
Animal Nutrition and Physiology
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Evaluation of toxicity of feed additive for highly productive animals — Irina V. Lunegova, A. M. Lunegov, et al. · Pharmacy Formulas (2024) | TGRS Research Map | TGRS