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Letters to the editor Specify where attrition is The title of the article “Many Researchers Leave Science within 5 Years” is misleading. The studies referenced in the article applied to academic careers. The title and the article itself should have made that clear. Chris Erickson Willard, Utah Considering noncanonical DNA structures for a DNA-based computer Computer chip makers are in a perpetual struggle to engineer the next generation of microprocessors. Currently used silicon-based microprocessors will soon reach their limits of memory, miniaturization, energy efficiency, speeds, and processing capabilities. Chip manufacturers need to find a new material to fabricate future microchips. It seems that DNA might become that material. DNA computer-based research is still a long way from being perfected; however, the double-stranded (ds) DNA molecule is able to store billions of times the data that present-day computers can. DNA computing research employs the principles of molecular biology, biochemistry, and nanotechnology.