Multiple Sclerosis Patient Macrophages Impaired Metabolism Leads to an Altered Response to Activation Stimuli
Our results show an intrinsic defect of MS patient macrophages, reminiscent of innate immune cell memory in MS, lifting macrophage importance in the disease and as potential therapeutic targets.
Authors
- Bruno Stankoff (ORCID: https://orcid.org/0000-0002-9631-4674)
- Farid Ichou (ORCID: https://orcid.org/0000-0001-6293-5133)
- Jennifer Fransson (ORCID: https://orcid.org/0000-0003-4762-901X)
- Maharajah Ponnaiah (ORCID: https://orcid.org/0000-0001-7761-4228)
- Céline Louapre (ORCID: https://orcid.org/0000-0002-4987-1531)
- Élisabeth Maillart (ORCID: https://orcid.org/0000-0001-7699-0328)
- Violetta Zujovic (ORCID: https://orcid.org/0000-0002-2741-6052)
- Fanny Mochel (ORCID: https://orcid.org/0000-0003-3970-3486)
- Arnaud Gloaguen
- Bertrand Fontaine (ORCID: https://orcid.org/0000-0003-4449-8683)
- Corinne Bachelin
- Léna Guillot‐Noël (ORCID: https://orcid.org/0000-0002-0287-3361)
- Arthur Tenenhaus
Institutions
- Centre National de la Recherche Scientifique (FR)
- Inserm (FR)
- Université Paris-Saclay (FR)
- Sorbonne Université (FR)
- Institut du Cerveau (FR)
Publication Details
- Journal
- Neurology Neuroimmunology & Neuroinflammation
- Published
- 2024-10-28
- DOI
- https://doi.org/10.1212/nxi.0000000000200312
- Citations
- 9
- Primary Topic
- Immune responses and vaccinations
- Type
- article
- Field-Weighted Citation Impact
- 2.16
Funders
- Sanofi
- Biogen
- Teva Pharmaceutical Industries
- Agence Nationale de la Recherche