Integrated analysis of bulk and single-cell RNA sequencing reveals the impact of nicotinamide and tryptophan metabolism on glioma prognosis and immunotherapy sensitivity
Our study evaluated the effects of nicotinamide and tryptophan metabolism on the prognosis and tumor immune microenvironment of glioma, which can help predict the prognosis and sensitivity to immunotherapy of glioma.
Authors
- Boduan Xiao (ORCID: https://orcid.org/0000-0003-0564-9944)
- Yuemeng Ji (ORCID: https://orcid.org/0000-0002-8641-4276)
- Shaochong Lin
- Man Qiu
- Shen Gao (ORCID: https://orcid.org/0000-0002-4376-6706)
- Xiaofeng Fang (ORCID: https://orcid.org/0000-0003-1161-9186)
- Xiangtong Zhang (ORCID: https://orcid.org/0000-0001-9313-8794)
- Kai Zheng (ORCID: https://orcid.org/0000-0002-6248-6275)
- Haopeng Zhang (ORCID: https://orcid.org/0000-0002-2229-2927)
- Sen Wang (ORCID: https://orcid.org/0009-0005-2988-4510)
Institutions
- Tianjin University of Traditional Chinese Medicine (CN)
- Harbin Medical University (CN)
- Nankai University (CN)
- Second Hospital of Tianjin Medical University (CN)
- Xian Yang Central Hospital (CN)
- Xinyang Central Hospital (CN)
- First Affiliated Hospital of Harbin Medical University (CN)
- Tianjin Medical University (CN)
Publication Details
- Journal
- BMC Neurology
- Published
- 2024-10-28
- DOI
- https://doi.org/10.1186/s12883-024-03924-5
- Citations
- 2
- Primary Topic
- Glioma Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.88