Engineering exosomes from fibroblast growth factor 1 pre-conditioned adipose-derived stem cells promote ischemic skin flaps survival by activating autophagy
FEXO markedly improved the survivial rate of ischemic skin flaps through miR-183-5p/GPR137/Pi3k/Akt/mTOR axis, which would be a promising strategy to rescue ischemic skin flaps.
Authors
- Huimin Deng (ORCID: https://orcid.org/0000-0001-8834-8172)
- Fuman Cai (ORCID: https://orcid.org/0000-0002-7008-5922)
- Xiaoqiong Jiang
- Xu Shi (ORCID: https://orcid.org/0000-0001-8566-9552)
- Tianling Chen
- Feifei Lian
- Abdullah Al Mamun (ORCID: https://orcid.org/0000-0002-7363-5934)
- Xuanlong Zhang
- Gaoxiang Yu
- Xiaokun Li (ORCID: https://orcid.org/0000-0002-7121-5768)
- Jian Xiao (ORCID: https://orcid.org/0000-0001-7374-6506)
- Jiayi Huang (ORCID: https://orcid.org/0000-0002-5153-506X)
- Ningning Yang (ORCID: https://orcid.org/0000-0002-7827-7072)
- Haijuan Zhang (ORCID: https://orcid.org/0000-0001-5842-8251)
- Yingying Lai (ORCID: https://orcid.org/0009-0004-1000-351X)
- Kailiang Zhou
Institutions
- Wenzhou Medical University (CN)
- First Affiliated Hospital of Wenzhou Medical University (CN)
- Second Affiliated Hospital & Yuying Children's Hospital of Wenzhou Medical University (CN)
- Zhejiang Lab (CN)
Publication Details
- Journal
- Materials Today Bio
- Published
- 2024-10-28
- DOI
- https://doi.org/10.1016/j.mtbio.2024.101314
- Citations
- 9
- Primary Topic
- Extracellular vesicles in disease
- Type
- article
- Field-Weighted Citation Impact
- 2.10