Periodontal conditions and salivary microbiota are potential indicators to distinguish silicosis: an exploratory study
The silicosis group exhibited worse CAL, improved BOP and PD, which may be related to the gingival fibrosis found in this study. The composition of the oral microbiota underwent significant changes, accompanied by a decrease in diversity, in patients with silicosis. Our study indicates that respirable crystalline silica exposure affects oral health, and alterations of oral microbiota might be implicated in silicosis. We primarily identified Aggregatibacter and Catonella as the potential indicators to distinguish silicosis patients from healthy controls.
Authors
- Nanyu Luo
- Fangzhi Zhu
- Lei Lei (ORCID: https://orcid.org/0000-0001-5737-7528)
- Ting Zhong (ORCID: https://orcid.org/0000-0001-9507-8940)
- Shaoying Duan
- Meiying Shao (ORCID: https://orcid.org/0000-0002-3384-9508)
- Chenchen Zhang (ORCID: https://orcid.org/0000-0001-8563-5002)
- Tao Hu (ORCID: https://orcid.org/0000-0002-4123-2962)
- Jialiang Zhao
Institutions
- Sichuan University (CN)
- Stomatology Hospital (CN)
- State Key Laboratory of Oral Diseases
- Guangzhou Medical University (CN)
Publication Details
- Journal
- BMC Microbiology
- Published
- 2024-10-28
- DOI
- https://doi.org/10.1186/s12866-024-03594-w
- Citations
- 1
- Primary Topic
- Occupational and environmental lung diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.42
Funders
- National Natural Science Foundation of China
- Sichuan Province Science and Technology Support Program