In Vitro Assessment of the Neuroprotective Effects of Pomegranate (Punica granatum L.) Polyphenols Against Tau Phosphorylation, Neuroinflammation, and Oxidative Stress
Overall, our results attribute to PPs anti-inflammatory, antioxidant, anti-apoptotic, and anti-Tau-pathology potential. Future studies should aim to extend our knowledge of the potential role of PPs in Aβ<sub>1-42</sub>-induced neurodegeneration, particularly concerning its association with the tauopathy involved in AD.
Authors
- Mehdi Alami
- Charles Ramassamy (ORCID: https://orcid.org/0000-0002-3252-5878)
- Tamàs Fülöp (ORCID: https://orcid.org/0000-0001-5835-7449)
- Ton Bunt (ORCID: https://orcid.org/0000-0001-7659-3162)
- Hicham Berrougui (ORCID: https://orcid.org/0000-0002-0546-6534)
- Jacek M. Witkowski
- Abdelouahed Khalil (ORCID: https://orcid.org/0000-0003-0817-3160)
- Samira Boulbaroud (ORCID: https://orcid.org/0000-0002-1197-6610)
- Nada Zoubdane
- Kaoutar Boumezough (ORCID: https://orcid.org/0009-0005-9337-9260)
- Benoît Laurent (ORCID: https://orcid.org/0000-0002-4032-3213)
- Echarki Zerif
Institutions
- Université de Sherbrooke (CA)
- Institut National de la Recherche Scientifique (CA)
- Université Sultan Moulay Slimane (MA)
- Izumi Biosciences (US)
- Gdańsk Medical University (PL)
Publication Details
- Journal
- Nutrients
- Published
- 2024-10-28
- DOI
- https://doi.org/10.3390/nu16213667
- Citations
- 17
- Primary Topic
- Pomegranate: compositions and health benefits
- Type
- article
- Field-Weighted Citation Impact
- 5.26
Funders
- Canadian Institutes of Health Research