Comparative Efficacy of Frailty and Barthel Index in Predicting AKI in Critically Ill Geriatric Patients

Background: The Barthel Index describes functional independence and the FRAIL questionnare predicts fragility in theelderly, this comorbidity is a risk factor to develop acute kidney injury (AKI). Thisstudy, aimed to explore the association between Barthel Index, Fraility and AKI in a geriatric ICU population. Methods: In a retrospective cohort in the Hospital Civil of Guadalajara, elderly ICU patientswere recluted. Frailty was measured CFS and FRAIL questionnare, functional independence by Barthel Index and AKI by KDIGOguideline. We test the predictive capability of Barthel Index and Fraility to develop AKI by logistic regression analysis and predictive accuracy. Results: In a total of 207 geriatric ICU patients with mean age of 78 years, 48% being classified as frail and 60% developed AKI. AKI presented in 59.5% in the frailgroup, and in 30.9% of non-frail. The mean Barthel Index was 67, it has nocorrelation with the risk of AKI (p = 0.9). Frailty has a positive correlation with thedevelopment of AKI (adjusted odds ratio = 4.04, p < 0.001). ROC curve analysis 0.6432, further indicated that frailty predicts better the occurrence of AKI than the Barthel Index. Conclusion: Frailty is a good predictor of AKI in ICU elderly patients, and is better than the Barthel Index.