A 16-year evaluation of opportunistic lung cancer screening with low-dose CT in China: comparative findings between non-smokers and smokers
LDCT screening improves early LC detection and treatment outcomes for both individuals who smoked and individuals who never smoked. Significant differences exist in epidemiology, histologic type, and survival between these groups. The USPSTF and CGSL criteria miss a significant number of LC cases, particularly among individuals who never smoked. Integrating individuals who never smoked into LCS programs is essential, yet it comes with its own challenges, such as managing radiation risks, allocating resources effectively, and considering financial aspects. Consequently, there is an urgent need for LCS programs in China to better identify the "high-risk" non-smoker population susceptible to LC and to ensure that potential risks associated with screening are reduced.
Authors
- Li Zhang (ORCID: https://orcid.org/0000-0003-4559-1599)
- Shijun Zhao (ORCID: https://orcid.org/0000-0003-0245-5917)
- Kai Zhang (ORCID: https://orcid.org/0000-0002-2292-3696)
- Donghui Hou (ORCID: https://orcid.org/0000-0001-8749-4741)
- Haohua Zhu (ORCID: https://orcid.org/0000-0002-7914-0289)
- Li Liu (ORCID: https://orcid.org/0000-0002-9678-9653)
- Jianwei Wang (ORCID: https://orcid.org/0000-0002-9511-0952)
- Yanyan Tang (ORCID: https://orcid.org/0000-0002-3328-3639)
- Zhou Lina (ORCID: https://orcid.org/0000-0003-3586-483X)
- Min Liang (ORCID: https://orcid.org/0000-0002-8354-1093)
- Yao Huang (ORCID: https://orcid.org/0000-0002-0866-1562)
- Ning Wu (ORCID: https://orcid.org/0000-0002-8220-5274)
- Zhijian Xu
- Wei Tang (ORCID: https://orcid.org/0000-0003-3091-0374)
- Fei Wang (ORCID: https://orcid.org/0000-0003-4073-4933)
- Qi Linlin
Institutions
- Capital Medical University (CN)
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Beijing Chao-Yang Hospital, Capital Medical University (CN)
- National Cancer Center (US)
- National Clinical Research (US)
Publication Details
- Journal
- BMC Cancer
- Published
- 2024-10-28
- DOI
- https://doi.org/10.1186/s12885-024-13056-1
- Citations
- 9
- Primary Topic
- Lung Cancer Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 3.77
Funders
- Cancer Foundation of China