Is pulmonary vascular remodeling an intermediate link between hyperglycemia and adverse outcomes in patients with idiopathic pulmonary arterial hypertension? Insights from a multi-center cohort study
SHR is positively associated with clinical worsening in patients with IPAH. The association appeared to be partially mediated through the pathway of pulmonary vascular remodeling, indicating that SHR may serve as a valuable indicator for providing additional risk information.
Authors
- Zhihui Zhao (ORCID: https://orcid.org/0000-0002-3105-092X)
- Zhihua Huang (ORCID: https://orcid.org/0000-0003-4011-8743)
- Yansong Guo
- Anqi Duan (ORCID: https://orcid.org/0000-0001-5829-9066)
- Qing Zhao (ORCID: https://orcid.org/0000-0003-3476-3906)
- Sicheng Zhang (ORCID: https://orcid.org/0000-0001-9175-3187)
- Peter Ping Lin (ORCID: https://orcid.org/0000-0002-6869-9490)
- Sicong Li (ORCID: https://orcid.org/0009-0000-4456-5845)
- Manqing Luo (ORCID: https://orcid.org/0000-0002-5706-1432)
- Yijia Wang (ORCID: https://orcid.org/0009-0009-1739-1822)
- Luyang Gao (ORCID: https://orcid.org/0000-0001-8046-8268)
- Qixian Zeng (ORCID: https://orcid.org/0000-0001-6855-995X)
- Qunying Xi (ORCID: https://orcid.org/0000-0003-1013-7775)
- Zhihong Liu (ORCID: https://orcid.org/0000-0001-6093-0726)
- Qin Luo (ORCID: https://orcid.org/0000-0002-1351-7231)
- Tao Yang
- Xin Li (ORCID: https://orcid.org/0000-0003-3175-5724)
Institutions
- Fujian Medical University (CN)
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Fujian Provincial Hospital (CN)
- Fu Wai Hospital (CN)
Publication Details
- Journal
- Cardiovascular Diabetology
- Published
- 2024-10-28
- DOI
- https://doi.org/10.1186/s12933-024-02476-9
- Citations
- 6
- Primary Topic
- Pulmonary Hypertension Research and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 2.51
Funders
- Chinese Academy of Medical Sciences