Serum Irisin, Myostatin, and Myonectin Correlate with Metabolic Health Markers, Liver Disease Progression, and Blood Pressure in Patients with Metabolic Dysfunction-Associated Fatty Liver Disease and Hypertension
In conclusion, the myokine profile in patients with MASLD and HTN correlates both with the severity of MASLD and the parameters characteristic of metabolic health, suggesting the possible contribution of altered irisin, myonectin, and myostatin concentrations to the occurrence of cardiometabolic risks in patients with MASLD.
Authors
- Elvira M. Mamutova
- Anton R. Kiselev (ORCID: https://orcid.org/0000-0003-3967-3950)
- V. A. Metelskaya (ORCID: https://orcid.org/0000-0001-8665-9129)
- A. F. Sheptulina (ORCID: https://orcid.org/0000-0001-7230-0780)
- Anastasia Yu. Elkina
- Y. S. Timofeev
- Oxana M. Drapkina (ORCID: https://orcid.org/0000-0003-0323-2635)
Institutions
- Moscow State University of Medicine and Dentistry (RU)
- National Research Center for Preventive Medicine (RU)
- Saratov State Medical University (RU)
Publication Details
- Journal
- Metabolites
- Published
- 2024-10-28
- DOI
- https://doi.org/10.3390/metabo14110584
- Citations
- 8
- Primary Topic
- Adipose Tissue and Metabolism
- Type
- article
- Field-Weighted Citation Impact
- 2.61
Funders
- Russian Science Foundation