Numerical solution of the forward Kolmogorov equations in population genetics using Eta functions

This paper introduces a new numerical method for solving forward Kolmogorov equations in population genetics . Since there's no simple analytical expression for the distribution of allele frequencies (DAF), we use these equations to derive it. The accuracy of solving these equations depends on the choice of base functions, so we use Eta-based functions for better approximations. By employing the operational matrix of integral, we simplify the partial differential equation to an algebraic one. The method's error bounds, stability, and validity are demonstrated through numerical examples. Finally, we apply this method to analyze the behavior of forward Kolmogorov equations under various evolutionary forces.

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Publication Details

Journal
Applied Numerical Mathematics
Published
2024-10-28
DOI
https://doi.org/10.1016/j.apnum.2024.10.013
Citations
1
Primary Topic
Cosmology and Gravitation Theories
Type
article
Field-Weighted Citation Impact
0.33

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article

Numerical solution of the forward Kolmogorov equations in population genetics using Eta functions

Somayeh Mashayekhi, S. Sedaghat
1 citations
Applied Numerical Mathematics
Cosmology and Gravitation Theories
0.33
article

Numerical solution of the forward Kolmogorov equations in population genetics using Eta functions

Somayeh Mashayekhi, S. Sedaghat
article en
1 citations

Abstract

This paper introduces a new numerical method for solving forward Kolmogorov equations in population genetics . Since there's no simple analytical expression for the distribution of allele frequencies (DAF), we use these equations to derive it. The accuracy of solving these equations depends on the choice of base functions, so we use Eta-based functions for better approximations. By employing the operational matrix of integral, we simplify the partial differential equation to an algebraic one. The method's error bounds, stability, and validity are demonstrated through numerical examples. Finally, we apply this method to analyze the behavior of forward Kolmogorov equations under various evolutionary forces.

Applied Numerical MathematicsVol. 208
Kennesaw State University (US), Buein Zahra Technical University (IR)
National Science Foundation
Openalex Percentile: Top 34%
Cosmology and Gravitation Theories
0.33
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