A Study of the Role of Statins in the Treatment of Coronary Heart Disease

Statins, as hydroxymethylglutaryl coenzyme A reductase inhibitors, have a significant effect on lowering cholesterol, and are widely used in the clinical treatment of cardiovascular and cerebrovascular diseases, and are potent drugs for the prevention and treatment of coronary heart disease. Recent studies have shown that statins also have other effects, such as lowering blood pressure, lowering blood glucose, stabilizing atherosclerotic plaques, slowing down the proliferation and migration of smooth muscle cells, anti-inflammatory and antihypertensive, etc., which are very significant. This paper addresses the physicochemical properties, pharmacological effects, adverse effects, and therapeutic applications of statins in the treatment of cardiovascular diseases (coronary heart disease).

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Publication Details

Journal
Journal of Clinical Medicine Research
Published
2024-10-24
DOI
https://doi.org/10.32629/jcmr.v5i3.2767
Primary Topic
Lipoproteins and Cardiovascular Health
Type
article
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article

A Study of the Role of Statins in the Treatment of Coronary Heart Disease

Hao Yang Tan, Xinyue Feng, Junshu Wang
Journal of Clinical Medicine Research
Lipoproteins and Cardiovascular Health
article

A Study of the Role of Statins in the Treatment of Coronary Heart Disease

Hao Yang Tan, Xinyue Feng, Junshu Wang
article en

Abstract

Statins, as hydroxymethylglutaryl coenzyme A reductase inhibitors, have a significant effect on lowering cholesterol, and are widely used in the clinical treatment of cardiovascular and cerebrovascular diseases, and are potent drugs for the prevention and treatment of coronary heart disease. Recent studies have shown that statins also have other effects, such as lowering blood pressure, lowering blood glucose, stabilizing atherosclerotic plaques, slowing down the proliferation and migration of smooth muscle cells, anti-inflammatory and antihypertensive, etc., which are very significant. This paper addresses the physicochemical properties, pharmacological effects, adverse effects, and therapeutic applications of statins in the treatment of cardiovascular diseases (coronary heart disease).

Journal of Clinical Medicine ResearchVol. 5(3)
Soochow University (CN)
Good health and well-being
Openalex Percentile: Top 64%
Lipoproteins and Cardiovascular Health
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A Study of the Role of Statins in the Treatment of Coronary Heart Disease — Hao Yang Tan, Xinyue Feng, et al. · Journal of Clinical Medicine Research (2024) | TGRS Research Map | TGRS