Effects of Abelmoschus manihot (L.) and its combination with irbesartan in the treatment of diabetic nephropathy via the gut–kidney axis
The present study provides experimental evidence that HKC regulates the gut microbiota, circulating metabolites, and renal gene activities, which are useful for better understanding of the action mechanisms of <i>A. manihot</i> in the treatment of DN through the gut-kidney axis.
Authors
- Jingjing Xu (ORCID: https://orcid.org/0000-0001-5499-0191)
- Haitao Ge
- Harvest F. Gu (ORCID: https://orcid.org/0000-0003-4578-5449)
- Rengui Saxu
- Haitao Tang (ORCID: https://orcid.org/0000-0001-7531-0458)
- Yuhui Song (ORCID: https://orcid.org/0000-0002-5087-4684)
- Hongmei Yu (ORCID: https://orcid.org/0000-0002-8279-7513)
- Nan Li (ORCID: https://orcid.org/0000-0002-0575-371X)
- Wei Tang (ORCID: https://orcid.org/0009-0002-5704-7806)
- Xu Cui
- Siyuan Cui (ORCID: https://orcid.org/0000-0003-0560-2388)
Institutions
- Jiangnan University (CN)
- Nanjing University of Chinese Medicine (CN)
- China Pharmaceutical University (CN)
- Lianyungang Runzhong Pharmaceutical (China) (CN)
- Jiangsu Province Hospital (CN)
- Wuxi People's Hospital (CN)
- Nanjing Medical University (CN)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2024-10-28
- DOI
- https://doi.org/10.3389/fphar.2024.1424968
- Citations
- 6
- Primary Topic
- Gut microbiota and health
- Type
- article
- Field-Weighted Citation Impact
- 1.40
Funders
- National Natural Science Foundation of China
- University-Industry Cooperation Research Project in Jiangsu