Effect of anti-inflammatory molecules from food on organoids derived from adenomatous polyps of FAP subjects

QER, EGG, and FIS can be easily taken from foods or dietary supplements, show toxicity on PDOs derived from adenomatous polyps, while they are known to be harmless on normal cells. Diets enriched with these substances could be potential supplemental treatments to reduce the risk of CRC in individuals with FAP.

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Publication Details

Journal
Tumori Journal
Published
2024-10-27
DOI
https://doi.org/10.1177/03008916241291301
Primary Topic
Genetic factors in colorectal cancer
Type
article
Field-Weighted Citation Impact
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article

Effect of anti-inflammatory molecules from food on organoids derived from adenomatous polyps of FAP subjects

Massimo Milione, Marco Vitellaro, Francesco Segrado, Susanna Zanutto et al.
Tumori Journal
Genetic factors in colorectal cancer
article

Effect of anti-inflammatory molecules from food on organoids derived from adenomatous polyps of FAP subjects

Massimo Milione, Marco Vitellaro, Francesco Segrado, Susanna Zanutto, Oscar Illescas, Stefano Signoroni, Manuela Gariboldi, Antonino Belfiore, Giovanna Sabella, Maria Teresa Ricci, Vito Ladisa, Luca Varinelli, C. Brignola, Patrizia Pasanisi, Davide Battistessa, Irene Cafferati
article en

Abstract

QER, EGG, and FIS can be easily taken from foods or dietary supplements, show toxicity on PDOs derived from adenomatous polyps, while they are known to be harmless on normal cells. Diets enriched with these substances could be potential supplemental treatments to reduce the risk of CRC in individuals with FAP.

Tumori Journal
Fondazione IRCCS Istituto Nazionale dei Tumori (IT)
Good health and well-being
Openalex Percentile: Top 69%
Genetic factors in colorectal cancer
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