Utilization of Hepatitis C Virus‐Infected Donor Hearts in Two Children and Two Young Adults: Initial Experience at a Pediatric Transplant Center
This case series details the successful multidisciplinary implementation of a protocol to accept cardiac allografts from HCV NAT+ donors for transplantation into HCV negative recipients at our pediatric transplant center. With the limited donor pool in pediatrics and the morbidity associated with prolonged durations on the transplant waitlist, pediatric centers should consider utilizing organs from HCV NAT+ donors to broaden the donor pool. Future work should evaluate other organs beyond heart and optimal timing and duration of direct acting antiviral therapy.
Authors
- Sharon Chen (ORCID: https://orcid.org/0000-0002-0576-0856)
- Hayley A. Gans (ORCID: https://orcid.org/0000-0001-9190-263X)
- Michael Ma (ORCID: https://orcid.org/0000-0002-1367-2071)
- Lauren M. Puckett (ORCID: https://orcid.org/0000-0003-1558-2739)
- E. Profita (ORCID: https://orcid.org/0000-0003-1578-3346)
- Sruti Nadimpalli (ORCID: https://orcid.org/0000-0003-0614-1720)
- Lauren E. Kushner (ORCID: https://orcid.org/0000-0003-2626-316X)
- Sharon Chen (ORCID: https://orcid.org/0000-0002-3705-258X)
- Joanne Lee (ORCID: https://orcid.org/0000-0002-8008-6910)
Institutions
- Lucile Packard Children's Hospital (US)
- Stanford University (US)
Publication Details
- Journal
- Pediatric Transplantation
- Published
- 2024-10-27
- DOI
- https://doi.org/10.1111/petr.14879
- Primary Topic
- Hepatitis C virus research
- Type
- article
- Field-Weighted Citation Impact
- 0.00