Enhancing longevity: the additional benefits of vaccination in older adults

Vaccination of older people (over age 60) reduces the impact of some preventable microbial diseases but has additional benefits including reducing cancer, reducing dementia and preventing cardiovascular and cerebrovascular disease. For instance, one study found herpes zoster vaccination reduces incident dementia by up to 28% over the subsequent 7 years. The mechanisms behind these additional benefits are being defined but likely include reduced inflammation and specific targeting of pathogenic proteins. These additional benefits emphasise the importance of a whole-of-life approach to vaccination.