Pilot study on the impact of HIFU treatment on miRNA profiles in vaginal secretions of uterine fibroids and adenomyosis patients
HIFU treatment altered miRNA profiles in fibroids/adenomyosis patients. Notably, hsa-miR-7977, hsa-miR-155-5p, hsa-miR-191-5p, and hsa-miR-223-3p showed significant changes in fibroid cases, except in low-energy treatments. hsa-miR-7977 consistently decreased post-treatment, while hsa-miR-155-5p decreased in the least efficient cases. Further research is needed for validation.
Authors
- Ting‐Chang Chang (ORCID: https://orcid.org/0000-0002-5301-6693)
- Jun-Jie Hong
- Chao‐Min Cheng (ORCID: https://orcid.org/0000-0002-8644-1960)
- L. Perera (ORCID: https://orcid.org/0000-0003-0823-1631)
- Wei‐Chun Chen (ORCID: https://orcid.org/0000-0002-6515-0996)
- Mei-Hsiu Cheng
Institutions
- Chang Gung University (TW)
- National Tsing Hua University (TW)
- Chang Gung Memorial Hospital (TW)
- Linkou Chang Gung Memorial Hospital (TW)
Publication Details
- Journal
- International Journal of Hyperthermia
- Published
- 2024-10-27
- DOI
- https://doi.org/10.1080/02656736.2024.2418426
- Citations
- 4
- Primary Topic
- Endometriosis Research and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 2.15
Funders
- Chang Gung Medical Foundation
- National Tsing Hua University