Blocking the <scp>HIF</scp>‐1α/glycolysis axis inhibits allergic airway inflammation by reducing <scp>ILC2</scp> metabolism and function
The HIF-1α/glycolysis axis is critical for controlling ILC2 responses in allergic airway inflammation and has potential immunotherapeutic value in asthma.
Authors
- Xinyao Li (ORCID: https://orcid.org/0000-0001-8683-3019)
- Hengbiao Sun
- Yuxiong Guo (ORCID: https://orcid.org/0000-0002-4914-8124)
- Yumei He (ORCID: https://orcid.org/0000-0003-4745-3210)
- Zhibin Zhao (ORCID: https://orcid.org/0000-0002-8994-3106)
- Ju Qiu (ORCID: https://orcid.org/0000-0002-1543-5678)
- Xiaogang Zhang (ORCID: https://orcid.org/0009-0002-6634-9267)
- Jingping Liu (ORCID: https://orcid.org/0000-0001-8364-639X)
- Junyu He (ORCID: https://orcid.org/0000-0002-6950-4966)
- Zhengcong Huang
- Tian-Ci Wang
- Guilang Zheng
Institutions
- Third Affiliated Hospital of Southern Medical University (CN)
- Shanghai Institute of Nutrition and Health (CN)
- Cell Technology (China) (HK)
- Guangdong Academy of Medical Sciences (CN)
- Guangdong Provincial People's Hospital (CN)
- Southern Medical University (CN)
Publication Details
- Journal
- Allergy
- Published
- 2024-10-27
- DOI
- https://doi.org/10.1111/all.16361
- Citations
- 29
- Primary Topic
- IL-33, ST2, and ILC Pathways
- Type
- article
- Field-Weighted Citation Impact
- 6.97
Funders
- National Natural Science Foundation of China
- National Natural Science Foundation of China-Guangdong Joint Fund