Treatment Effect Measures Under Nonproportional Hazards
'Treatment effect measures under nonproportional hazards' by Snapinn et al. (Pharmaceutical Statistics, 22, 181-193) recently proposed some novel estimates of treatment effect for time-to-event endpoints. In this note, we clarify three points related to the proposed estimators that help to elucidate their properties. We hope that their work, and this commentary, will motivate further discussion concerning treatment effect measures that do not require the proportional hazards assumption.
Authors
- Michael Sweeting (ORCID: https://orcid.org/0000-0003-0980-8965)
- Dan Jackson (ORCID: https://orcid.org/0000-0002-4963-8123)
- Rose Baker (ORCID: https://orcid.org/0000-0003-3555-3425)
Institutions
- AstraZeneca (United Kingdom) (GB)
- University of Salford (GB)
Publication Details
- Journal
- Pharmaceutical Statistics
- Published
- 2024-10-27
- DOI
- https://doi.org/10.1002/pst.2449
- Citations
- 2
- Primary Topic
- Statistical Methods in Clinical Trials
- Type
- article
- Field-Weighted Citation Impact
- 1.42