Progranulin derivative attenuates lung neutrophilic infiltration from diesel exhaust particle exposure

FBAC reduced neutrophilic inflammation exaggerated by DEP exposure in a mouse model of allergic airway inflammation by reducing oxidative stress. PGRN and PGRN-derived proteins may be novel therapeutic agents in attenuating asthma exacerbation induced by air pollutant exposure.

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Publication Details

Journal
Allergy
Published
2024-10-27
DOI
https://doi.org/10.1111/all.16362
Citations
4
Primary Topic
Air Quality and Health Impacts
Type
article
Field-Weighted Citation Impact
1.26

Funders

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article

Progranulin derivative attenuates lung neutrophilic infiltration from diesel exhaust particle exposure

Sin‐Jeong Kim, Yi Hong, Hyun Jae Shim, Min Ju Pyo et al.
4 citations
Allergy
Air Quality and Health Impacts
1.26
article

Progranulin derivative attenuates lung neutrophilic infiltration from diesel exhaust particle exposure

Sin‐Jeong Kim, Yi Hong, Hyun Jae Shim, Min Ju Pyo, Kyomoon Koo, Hyouk‐Soo Kwon, A. Ryang Lee, Ji‐Hyang Lee, Yura Ha, Mini Jeong, You Sook Cho, Keun‐Ai Moon
article en
4 citations

Abstract

FBAC reduced neutrophilic inflammation exaggerated by DEP exposure in a mouse model of allergic airway inflammation by reducing oxidative stress. PGRN and PGRN-derived proteins may be novel therapeutic agents in attenuating asthma exacerbation induced by air pollutant exposure.

AllergyVol. 80(3)
Ulsan College (KR), Asan Medical Center (KR), University of Ulsan (KR)
National Research Foundation, Korea Health Industry Development Institute, National Research Foundation of Korea, Ministry of Science and ICT, South Korea
Openalex Percentile: Top 21%
Air Quality and Health Impacts
1.26
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