Childhood trajectories of emotional and behavioral difficulties are related to polygenic liability for mood and anxiety disorders
Genetic risk for mood disorders and related traits contribute to both a higher baseline level of, and a more rapid increase in, emotional and behavioral difficulties across early and middle childhood, with some indications for disorder-specific profiles. Our findings may inform research on developmental pathways to emotional disorders and the improvement of initiatives for early identification and targeted intervention.
Authors
- Nora R. Bakken (ORCID: https://orcid.org/0000-0003-2553-452X)
- Piotr Jahołkowski (ORCID: https://orcid.org/0000-0001-9408-3107)
- Pravesh Parekh (ORCID: https://orcid.org/0000-0002-1930-1167)
- Ole A. Andreassen (ORCID: https://orcid.org/0000-0002-4461-3568)
- Viktoria Birkenæs (ORCID: https://orcid.org/0000-0003-3194-1535)
- Evgeniia Frei (ORCID: https://orcid.org/0009-0008-6405-9059)
- Alexandra Havdahl (ORCID: https://orcid.org/0000-0002-9268-0423)
- Espen Hagen (ORCID: https://orcid.org/0000-0002-1321-5970)
- Alexey A. Shadrin (ORCID: https://orcid.org/0000-0002-7467-250X)
- Martin Tesli (ORCID: https://orcid.org/0000-0001-7495-5545)
- Guy Hindley (ORCID: https://orcid.org/0000-0003-1666-4701)
- Laurie J. Hannigan (ORCID: https://orcid.org/0000-0003-3123-5411)
- Nadine Parker (ORCID: https://orcid.org/0000-0002-8369-0152)
- Laura Hegemann (ORCID: https://orcid.org/0000-0002-7398-3760)
- Elizabeth C. Corfield (ORCID: https://orcid.org/0000-0002-0119-157X)
Institutions
- Oslo University Hospital (NO)
- Norwegian Institute of Public Health (NO)
- University of Oslo (NO)
- University of Bristol (GB)
- Lovisenberg Diakonale Høgskole (NO)
Publication Details
- Journal
- Journal of Child Psychology and Psychiatry
- Published
- 2024-10-27
- DOI
- https://doi.org/10.1111/jcpp.14063
- Citations
- 6
- Primary Topic
- Child and Adolescent Psychosocial and Emotional Development
- Type
- article
- Field-Weighted Citation Impact
- 3.83
Funders
- Stiftelsen Kristian Gerhard Jebsen
- Sunovion
- Trond Mohn stiftelse
- European Commission
- Helse- og Omsorgsdepartementet
- Novo Nordisk
- Universitetet i Bergen
- Universitetet i Oslo
- Norges Forskningsråd
- H. Lundbeck A/S
- EEA Grants/Norway Grants
- HORIZON EUROPE Framework Programme
- Helse Sør-Øst RHF
- Norwegian Institute of Public Health