Baseline Clinical Factors Associated with Cessation of Growth Hormone Therapy in Patients with Severe Growth Hormone Deficiency - Real World Evidence

In this real-world investigation of patients with severe GH deficiency, over two in five individuals who discontinued GH therapy cited the absence of perceived benefits. We show a borderline association of female gender with GH cessation and large population-based studies will be needed to investigate this and other causes of GH cessation.

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Publication Details

Journal
International Journal of Endocrinology and Metabolism
Published
2024-10-27
DOI
https://doi.org/10.5812/ijem-147825
Primary Topic
Growth Hormone and Insulin-like Growth Factors
Type
article
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article

Baseline Clinical Factors Associated with Cessation of Growth Hormone Therapy in Patients with Severe Growth Hormone Deficiency - Real World Evidence

Kazeem Adeleke, Thozhukat Sathyapalan, Harshal Deshmukh, Emmanuel Ssemmondo et al.
International Journal of Endocrinology and Metabolism
Growth Hormone and Insulin-like Growth Factors
article

Baseline Clinical Factors Associated with Cessation of Growth Hormone Therapy in Patients with Severe Growth Hormone Deficiency - Real World Evidence

Kazeem Adeleke, Thozhukat Sathyapalan, Harshal Deshmukh, Emmanuel Ssemmondo, Remi Akinyombo, Shani Brooks, Nageswary Nadarajah
article en

Abstract

In this real-world investigation of patients with severe GH deficiency, over two in five individuals who discontinued GH therapy cited the absence of perceived benefits. We show a borderline association of female gender with GH cessation and large population-based studies will be needed to investigate this and other causes of GH cessation.

International Journal of Endocrinology and MetabolismVol. 22(3)
University of Hull (GB), University of Cambridge (GB)
Good health and well-being
Openalex Percentile: Top 70%
Growth Hormone and Insulin-like Growth Factors
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