Diversity of heart failure phenotypes in transthyretin amyloid cardiomyopathy. More than just heart failure with preserved ejection fraction
This study revealed significant variability in HF phenotypes among patients with ATTR-CM, from HFpEF without LV dilatation to HFrEF with severe LV dilatation. Relying solely on HFpEF for screening may lead to under-diagnosis. These findings suggest the need for more comprehensive diagnostic criteria beyond echocardiographic measures to improve ATTR-CM detection and management.
Authors
- Anneline S.J.M. te Riele (ORCID: https://orcid.org/0000-0003-1115-6193)
- Pim van der Harst (ORCID: https://orcid.org/0000-0002-2713-686X)
- Anouk Achten (ORCID: https://orcid.org/0009-0005-0763-7551)
- Sandra Sanders‐van Wijk (ORCID: https://orcid.org/0000-0002-6291-6167)
- Steven A. Muller (ORCID: https://orcid.org/0000-0002-2674-8709)
- Manon G. van der Meer (ORCID: https://orcid.org/0009-0008-5839-167X)
- Vanessa P. M. van Empel (ORCID: https://orcid.org/0000-0002-6864-0296)
- Marish I.F.J. Oerlemans (ORCID: https://orcid.org/0000-0003-3166-518X)
- Christian Knackstedt (ORCID: https://orcid.org/0000-0002-5457-3010)
- J. Peter van Tintelen (ORCID: https://orcid.org/0000-0003-3854-6749)
Institutions
- Utrecht University (NL)
- University Medical Center Utrecht (NL)
- Maastricht University (NL)
- Netherlands Heart Institute (NL)
- Zuyderland Medisch Centrum (NL)
- ERN GUARD-Heart (NL)
Publication Details
- Journal
- Annals of Medicine
- Published
- 2024-10-26
- DOI
- https://doi.org/10.1080/07853890.2024.2418965
- Citations
- 8
- Primary Topic
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Type
- article
- Field-Weighted Citation Impact
- 1.87