Short and long-term effects of kidney donation on mineral and bone metabolism
The abrupt decline in kidney mass is associated with an increase in PTH and FGF23 that is not explained by phosphate retention. In a long-term evaluation, LKD showed a sustained drop in GFR, with lower serum calcitriol and Klotho, and higher PTH. The effects of these changes should be investigated in further studies.
Authors
- Elias David‐Neto (ORCID: https://orcid.org/0000-0002-3310-0484)
- Rosa Maria Affonso Moysés (ORCID: https://orcid.org/0000-0002-7902-2127)
- Vanda Jorgetti (ORCID: https://orcid.org/0000-0002-4824-8879)
- Wagner Vasques Dominguez (ORCID: https://orcid.org/0000-0003-3462-1860)
- Eduardo Jorge Duque (ORCID: https://orcid.org/0000-0002-5099-9727)
- Gustavo Fernandes Ferreira (ORCID: https://orcid.org/0000-0002-0036-0298)
- Fabiana Agena (ORCID: https://orcid.org/0000-0002-4526-4857)
- Francine Brambate Carvalhinho Lemos
- Myles Wolf
- Ivone B. Oliveira
Institutions
- Duke University (US)
- Clinical Research Institute (US)
- Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo (BR)
Publication Details
- Journal
- BMC Nephrology
- Published
- 2024-10-26
- DOI
- https://doi.org/10.1186/s12882-024-03827-0
- Primary Topic
- Dialysis and Renal Disease Management
- Type
- article
- Field-Weighted Citation Impact
- 0.00